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1

β1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury

Cordes, N, Seidler, J, Durzok, R, Geinitz, H, Brakebusch, C

Journal:

Year:

2005

Language:

english

File:

PDF, 392 KB

english, 2005

2

Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate

Wahlestedt, Martin, Erlandsson, Eva, Kristiansen, Trine, Lu, Rong, Brakebusch, Cord, Weissman, Irving L., Yuan, Joan, Martin-Gonzalez, Javier, Bryder, David

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 988 KB

english, 2017

3

The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain

Dino P. Leone, Karpagam Srinivasan, Cord Brakebusch, Susan K. McConnell

Journal:

Developmental Neurobiology

Year:

2010

Language:

english

File:

PDF, 13.13 MB

english, 2010

4

Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development

Xunwei Wu, Shaohua Li, Anna Chrostek-Grashoff, Aleksandra Czuchra, Hannelore Meyer, Peter D. Yurchenco, Cord Brakebusch

Journal:

Developmental Dynamics

Year:

2007

Language:

english

File:

PDF, 784 KB

english, 2007

5

Functional discrepancies between tumor necrosis factor and lymphotoxin α explained by trimer stability and distinct receptor interactions

Marcus Schuchmann, Sigrun Hess, Philip Bufler, Cord Brakebusch, David Wallach, Alan Porter, Gert Riethmüller, Hartmut Engelmann

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 793 KB

english, 1995

6

β1 integrins are not required for the maintenance of lymphocytes within intestinal epithelia

Jan Marsal, Cord Brakebusch, Gerd Bungartz, Reinhard Fässler, William W. Agace

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

7

Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection

Stefan Porubsky, Shijun Wang, Eva Kiss, Stefan Dehmel, Mahnaz Bonrouhi, Tatjana Dorn, Bruno Luckow, Cord Brakebusch, Hermann-Josef Gröne

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 790 KB

english, 2011

8

Hepatocyte-specific deletion of Cdc42 results in delayed liver regeneration after partial hepatectomy in mice

Haixin Yuan, Hong Zhang, Xunwei Wu, Zhe Zhang, Dan Du, Wenchao Zhou, Shuhua Zhou, Cord Brakebusch, Zhengjun Chen

Journal:

Year:

2009

Language:

english

File:

PDF, 1.92 MB

english, 2009

9

Rac1 is essential for phospholipase C-γ2 activation in platelets

Irina Pleines, Margitta Elvers, Amrei Strehl, Miroslava Pozgajova, David Varga-Szabo, Frauke May, Anna Chrostek-Grashoff, Cord Brakebusch, Bernhard Nieswandt

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 576 KB

english, 2009

10

Commentary 5

Dr Cord Brakebusch

Journal:

Experimental Dermatology

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

11

β1 integrin promotes but is not essential for metastasis of ras-myc transformed fibroblasts

Brakebusch, Cord, Wennerberg, Krister, Krell, Hans W, Weidle, Ulrich H, Sallmyr, Annahita, Johansson, Staffan, Fässler, Reinhard

Journal:

Year:

1999

Language:

english

File:

PDF, 1.56 MB

english, 1999

12

Rho GTPase function in tumorigenesis

R. Karlsson, E.D. Pedersen, Z. Wang, Cord Brakebusch

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2009

Language:

english

File:

PDF, 297 KB

english, 2009

13

FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Jennifer Block, Dennis Breitsprecher, Sonja Kühn, Moritz Winterhoff, Frieda Kage, Robert Geffers, Patrick Duwe, Jennifer L. Rohn, Buzz Baum, Cord Brakebusch, Matthias Geyer, Theresia E.B. Stradal, Jan

Journal:

Current Biology

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

14

Cdc42 is crucial for the maturation of primordial cell junctions in keratinocytes independent of Rac1

Dan Du, Esben Pedersen, Zhipeng Wang, Richard Karlsson, Zhengjun Chen, Xunwei Wu, Cord Brakebusch

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 1.63 MB

english, 2009

15

Rho GTPase function in development: How in vivo models change our view

Esben Pedersen, Cord Brakebusch

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 366 KB

english, 2012

16

Sequence and Chromosomal Localization of the Mouse Brevican Gene

Uwe Rauch, Hannelore Meyer, Cord Brakebusch, Constanze Seidenbecher, Eckart D. Gundelfinger, David R. Beier, Reinhard Fässler

Journal:

Year:

1997

Language:

english

File:

PDF, 183 KB

english, 1997

17

Isolation and Functional Characterization of the Human 90K Promoter

Cord Brakebusch, Irmingard Sures, Bahija Jallal, Kevin Mossie, Ornella Fusco, Stefano Iacobelli, Axel Ullrich

Journal:

Year:

1999

Language:

english

File:

PDF, 260 KB

english, 1999

18

Short arm region of laminin-5 γ2 chain: structure, mechanism of processing and binding to heparin and proteins

Takako Sasaki, Walter Göhring, Karlheinz Mann, Cord Brakebusch, Yoshihiko Yamada, Reinhard Fässler, Rupert Timpl

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 536 KB

english, 2001

19

Cdc42-Mediated Tubulogenesis Controls Cell Specification

Gokul Kesavan, Fredrik Wolfhagen Sand, Thomas Uwe Greiner, Jenny Kristina Johansson, Sune Kobberup, Xunwei Wu, Cord Brakebusch, Henrik Semb

Journal:

Year:

2009

Language:

english

File:

PDF, 3.01 MB

english, 2009

20

Cdc42 expression in keratinocytes is required for the maintenance of the basement membrane in skin

Xunwei Wu, Fabio Quondamatteo, Cord Brakebusch

Journal:

Year:

2006

Language:

english

File:

PDF, 6.23 MB

english, 2006

21

A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory

Ursula Haditsch, Dino P. Leone, Mélissa Farinelli, Anna Chrostek-Grashoff, Cord Brakebusch, Isabelle M. Mansuy, Susan K. McConnell, Theo D. Palmer

Journal:

Molecular and Cellular Neuroscience

Year:

2009

Language:

english

File:

PDF, 1.70 MB

english, 2009

22

Stage-Specific Control of Neural Crest Stem Cell Proliferation by the Small Rho GTPases Cdc42 and Rac1

Sebastian Fuchs, Dominik Herzog, Grzegorz Sumara, Stine Büchmann-Møller, Gianluca Civenni, Xunwei Wu, Anna Chrostek-Grashoff, Ueli Suter, Romeo Ricci, João B. Relvas, Cord Brakebusch, Lukas Sommer

Journal:

Year:

2009

Language:

english

File:

PDF, 2.72 MB

english, 2009

23

None of the integrins known to be present on the mouse egg or to be ADAM receptors are essential for sperm–egg binding and fusion

Zhi-Yong He, Cord Brakebusch, Reinhard Fässler, Jordan A Kreidberg, Paul Primakoff, Diana G Myles

Journal:

Developmental Biology

Year:

2003

Language:

english

File:

PDF, 442 KB

english, 2003

24

Functional Inactivation of a Fraction of Excitatory Synapses in Mice Deficient for the Active Zone Protein Bassoon

Wilko D. Altrock, Susanne tom Dieck, Maxim Sokolov, Alexander C. Meyer, Albrecht Sigler, Cord Brakebusch, Reinhard Fässler, Karin Richter, Tobias M. Boeckers, Heidrun Potschka, Claudia Brandt, Wolfgan

Journal:

Year:

2003

Language:

english

File:

PDF, 700 KB

english, 2003

25

Fetal and Adult Hematopoietic Stem Cells Require β1 Integrin Function for Colonizing Fetal Liver, Spleen, and Bone Marrow

Alexandre J Potocnik, Cord Brakebusch, Reinhard Fässler

Journal:

Year:

2000

Language:

english

File:

PDF, 436 KB

english, 2000

26

β1 Integrin Is Not Essential for Hematopoiesis but Is Necessary for the T Cell-Dependent IgM Antibody Response

Cord Brakebusch, Simon Fillatreau, Alexandre J Potocnik, Gerd Bungartz, Patricia Wilhelm, Marcus Svensson, Phil Kearney, Heinrich Körner, David Gray, Reinhard Fässler

Journal:

Year:

2002

Language:

english

File:

PDF, 598 KB

english, 2002

27

Interactions of the integrin subunit β1A with protein kinase B/Akt, p130Cas and paxillin contribute to regulation of radiation survival

Julia Seidler, Rita Durzok, Cord Brakebusch, Nils Cordes

Journal:

Radiotherapy and Oncology

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

28

Threonine 788 in integrin subunit β1 regulates integrin activation

Stina Nilsson, Dorota Kaniowska, Cord Brakebusch, Reinhard Fässler, Staffan Johansson

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 1.26 MB

english, 2006

29

182 β1-integrins in cell adhesion-mediated radioresistance: First emerging insights

N. Cordes, C. Brakebusch

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

30

Continuous Cell Injury Promotes Hepatic Tumorigenesis in Cdc42-Deficient Mouse Liver

Jolanda van Hengel, Petra D’Hooge, Bart Hooghe, Xunwei Wu, Louis Libbrecht, Rita De Vos, Fabio Quondamatteo, Martina Klempt, Cord Brakebusch, Frans van Roy

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 3.93 MB

english, 2008

31

Mouse as a Model Organism || The German Mouse Clinic – Running an Open Access Platform

Brakebusch, Cord, Pihlajaniemi, Taina

Year:

2011

Language:

english

File:

PDF, 632 KB

english, 2011

32

Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1

Huelsenbeck, Stefanie C., Roggenkamp, Dennis, May, Martin, Huelsenbeck, Johannes, Brakebusch, Cord, Rottner, Klemens, Ladwein, Markus, Just, Ingo, Fritz, Gerhard, Schmidt, Gudula, Genth, Harald

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

33

NADPH Oxidase Complex-Derived Reactive Oxygen Species, the Actin Cytoskeleton, and Rho GTPases in Cell Migration

Stanley, Alanna, Thompson, Kerry, Hynes, Ailish, Brakebusch, Cord, Quondamatteo, Fabio

Journal:

Antioxidants & Redox Signaling

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

34

Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of GTPases and Downregulation of Cadherin and Catenin Function

Clotilde Gimond, Arjan van der Flier, Sanne van Delft, Cord Brakebusch, Ingrid Kuikman, John G. Collard, Reinhard Fässler and Arnoud Sonnenberg

Journal:

The Journal of Cell Biology

Year:

1999

Language:

english

File:

PDF, 5.55 MB

english, 1999

35

β1 Integrin Is Essential for Teratoma Growth and Angiogenesis

Wilhelm Bloch, Erik Forsberg, Sylvia Lentini, Cord Brakebusch, Karl Martin, Hans W. Krell, Ulrich H. Weidle, Klaus Addicks and Reinhard Fässler

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 5.80 MB

english, 1997

36

The Fibronectin-Binding Integrins α5β1 and αvβ3 Differentially Modulate RhoA-GTP Loading, Organization of Cell Matrix Adhesions, and Fibronectin Fibrillogenesis

Erik H. J. Danen, Petra Sonneveld, Cord Brakebusch, Reinhard Fässler and Arnoud Sonnenberg

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 6.21 MB

english, 2002

37

The small GTPase Rac1 is required for smooth muscle contraction

Rahman, Awahan, Davis, Benjamin, Lövdahl, Cecilia, Hanumaiah, Veena T., Feil, Robert, Brakebusch, Cord, Arner, Anders

Journal:

The Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 706 KB

english, 2014

38

Mouse as a Model Organism ||

Brakebusch, Cord, Pihlajaniemi, Taina

Year:

2011

Language:

english

File:

PDF, 2.96 MB

english, 2011

39

Rac1-dependent recruitment of PAK2 to G 2 phase centrosomes and their roles in the regulation of mitotic entry

May, Martin, Schelle, Ilona, Brakebusch, Cord, Rottner, Klemens, Genth, Harald

Journal:

Year:

2014

Language:

english

File:

PDF, 4.35 MB

english, 2014

40

Rho GTPases and cancer

Li, Hui, Peyrollier, Karine, Kilic, Gülcan, Brakebusch, Cord

Journal:

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

41

Mouse Macrophages Completely Lacking Rho Subfamily GTPases (RhoA, RhoB, and RhoC) Have Severe Lamellipodial Retraction Defects, but Robust Chemotactic Navigation and Altered Motility

Königs, Volker, Jennings, Richard, Vogl, Thomas, Horsthemke, Markus, Bachg, Anne C., Xu, Yan, Grobe, Kay, Brakebusch, Cord, Schwab, Albrecht, Bähler, Martin, Knaus, Ulla G., Hanley, Peter J.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.99 MB

english, 2014

42

Neuronal Rac1 Is Required for Learning-Evoked Neurogenesis

Haditsch, U., Anderson, M. P., Freewoman, J., Cord, B., Babu, H., Brakebusch, C., Palmer, T. D.

Journal:

Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 4.13 MB

english, 2013

43

Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair

Xia, Jingjing, Swiercz, Jakub M., Bañón-Rodríguez, Inmaculada, Matković, Ivana, Federico, Giuseppina, Sun, Tianliang, Franz, Timo, Brakebusch, Cord H., Kumanogoh, Atsushi, Friedel, Roland H., Martín-B

Journal:

Developmental Cell

Year:

2015

Language:

english

File:

PDF, 8.23 MB

english, 2015

44

How to Bury the Dead: Elimination of Apoptotic Hair Cells from the Hearing Organ of the Mouse

Anttonen, Tommi, Belevich, Ilya, Kirjavainen, Anna, Laos, Maarja, Brakebusch, Cord, Jokitalo, Eija, Pirvola, Ulla

Journal:

Journal of the Association for Research in Otolaryngology

Year:

2014

Language:

english

File:

PDF, 12.13 MB

english, 2014

45

Essential and Distinct Roles for Cdc42 and Rac1 in the Regulation of Schwann Cell Biology during Peripheral Nervous System Development

Yves Benninger, Tina Thurnherr, Jorge A. Pereira, Sven Krause, Xunwei Wu, Anna Chrostek-Grashoff, Dominik Herzog, Klaus-Armin Nave, Robin J. M. Franklin, Dies Meijer, Cord Brakebusch, Ueli Suter and J

Journal:

The Journal of Cell Biology

Year:

2007

Language:

english

File:

PDF, 3.06 MB

english, 2007

46

The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro

Bray, Kristi, Brakebusch, Cord, Vargo-Gogola, Tracy

Journal:

Year:

2011

Language:

english

File:

PDF, 3.92 MB

english, 2011

47

Mice Lacking Desmocollin 1 Show Epidermal Fragility Accompanied by Barrier Defects and Abnormal Differentiation

Martyn Chidgey, Cord Brakebusch, Erika Gustafsson, Alan Cruchley, Chris Hail, Sarah Kirk, Anita Merritt, Alison North, Chris Tselepis, Jane Hewitt, Carolyn Byrne, Reinhard Fassler and David Garrod

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 4.02 MB

english, 2001

48

The Cysteine-Rich Domain of Human ADAM 12 Supports Cell Adhesion through Syndecans and Triggers Signaling Events That Lead to β1 Integrin-Dependent Cell Spreading

Kousuke Iba, Reidar Albrechtsen, Brent Gilpin, Camilla Fröhlich, Frosty Loechel, Anna Zolkiewska, Kazuhiro Ishiguro, Tetsuhito Kojima, Wei Liu, J. Kevin Langford, Ralph D. Sanderson, Cord Brakebusch,

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 4.69 MB

english, 2000

49

Tu1822 Deletion of Rho-A Within IECs Causes Intestinal Inflammation

Lopez-Posadas, Rocio, Becker, Christoph, Atreya, Raja, Watson, Alastair J., Brakebusch, Cord, Neurath, Markus F., Atreya, Imke

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 67 KB

english, 2015

50

Genetic Analysis of β1 Integrin "Activation Motifs" in Mice

Aleksandra Czuchra, Hannelore Meyer, Kyle R. Legate, Cord Brakebusch and Reinhard Fässler

Journal:

The Journal of Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.83 MB

english, 2006